Biochemical And Pre-Clinical Testing

The ELISA Based Assay is a competitive enzyme-labeled immunoassay for the quantitation of Aflatoxin (mycotoxins). Aspergillus flavus and A. parasiticus produce exclusively aflatoxin B1, B2, G1 and G2, and all the other aflatoxins are derivate of these four. Contaminations of herbs and Nutraceuticals can be hazardous for human beings.

Enzyme assays are carefully designed experimental procedures that have been developed to accurately gauge the level of activity or concentration of enzymes within biological or cellular systems.

Pro inflammatory cytokines are involved in various disease conditions and act as signaling molecules for immune system.

Skin irritation refers to the production of reversible damage to the skin occurring after exposure to a substance or mixture.

Genotoxicity testing is an integral component of toxicity evaluation for drugs as recommended by regulatory agencies in most countries.

Substances that cause adverse changes at the site of first contact (skin, eye, mucous membrane, respiratory tract etc.) after a single exposure can be categorized as irritant or corrosive substances, depending on the reversibility of the effects observed

Evaluation of small molecules, natural products using cell-based, biochemical and other assay platforms for efficacy studies

Cell migration assay is important biological process to assess embryonic development, wound repair, immune system functions, and the spread of cancer measuring the net migration of a cell population across a micro-porous membrane towards chemoattractant.

MTT assay gives general indication about cell viability, proliferation and cytotoxicity. The assay is considered as gold standard and employed to validate other methods through the reduction of tetrazolium compounds.

BVGLSL offer expert services to design and conduct toxicity studies with various routes of administration for different types of products, including pharmaceuticals, biopharmaceuticals, herbal products, and cosmetics. We follow both international and national guidelines for these tests. The studies are conducted in compliance with Good laboratory practices (GLP).